Antibiotics and Biochemicals
 
 

3-Amino-1, 2, 4-triazole 3-AT C2H4N4=84.08

3-AT is a competitive inhibitor of the product of the HIS3 gene, imidazoleglycerol-phosphate dehydratase. Imidazoleglycerol-phosphate dehydratase is an enzyme catalyzing the sixth step of histidine production.
 
 Reference Number Pack Size GBP (£)
 3AT010 10 g 6.40
 3AT025 25 g 11.60
 3AT100 100 g 29.20
     
 Specifications  
 Assay (HPLC) 98.6%
 Melting range 152 - 153 C�
 Loss on drying <0.2%
   
CAS 61-82-5

5-Aminolevulinic acid hydrochloride NH2CH2COCH2CH2COOH.HCl = 167.59
 
 Reference Number Pack Size

GBP (£)
 5ALA01 1 g 42.00
 5ALA05 5 g 154.00
 5ALA10 10 g 231.00
     
 Specifications  
 Assay (HPLC) 99.3%
 Melting range 148.2 - 149.6 C�
 Loss on drying <0.2%
 Residue on ignition 0.06%
   
CAS 5451-09-2

5-Fluoro Orotic Acid Monohydrate C5H3FN2O4.H2O = 192.1
 
 Reference Number Pack Size

GBP (£)
 5FOA01 1 g 21.00
 5FOA05 5 g 70.00
 5FOA10 10 g 131.00
     
 Specifications  
 Character Slight yellow crystalline powder
 Solubility Soluble in DMSO, slightly soluble in alcohol and methanol
 Assay (HPLC) 99%
 Loss on drying <0.2%
   
CAS 207291-81-4
R: 20/21/22 S: 26-36/37/39
Ampicillin Sodium C16H18N3O4SNa=371.4
 
 Reference Number Pack Size

GBP (£)
 AMP01 1 g 4.00
 AMP05 5 g 5.20
 AMP10 10 g 6.20
 AMP25 25 g 14.80
 AMP50 50 g 24.90
 AMP100 100 g 39.90
     
 Specifications  
 USP 25, Ph. Eur.  
Store dry at 2-8 C�
Soluble in water
Hygroscopic, protect against moisture
CAS 69-52-3
R: 42/44-36/37/38 S: 22-36/37-26

Canavanine Sulphate C5H14N4O7S=274.3

L-Canavanine is a toxic structural analogue of L-Arginine. The uptake of Canavanine leads to incorporation in protein in the place of Arginine, thereby producing structurally aberrant proteins that may not function properly. Both Canavanine and Arginine are imported into the cell by the same high affinity permease which is encoded by the CAN1 locus. Mutations and deletions in this CAN1 locus result in high level resistance to L-Canavanine.
 
 Reference Number Pack Size

GBP (£)
 CAN001 1 g 50.00
 CAN005 5 g 200.50
     
 Specifications  
 Appearance White to off white crystal
 Content 99.25%
 Water 0.45%
 Loss on drying ≤0.5%
 Residue on ignition ≤0.1%
 Heavy metals ≤10ppm
 
CAS 2219-31-0
R: 20/21/22 S: 36

Carbenicillin Disodium C17H16N2Na2O6S=422.4
 
 Reference Number Pack Size

GBP (£)
 CAR0005 5 g 14.00
 CAR0025 25 g 62.50
     
Store dry at 2-8 C�
Soluble in water
Hygroscopic, protect against moisture
CAS 69-52-3
R: 42/43 S: 22-36/37-26
 

Cefotaxime Sodium C16H1N5NaO7S2=477.4
 
 Reference Number Pack Size

GBP (£)
 CEFO001 1 g 22.50
 CEFO005 5 g 30.00
 CEFO025 25 g 135.00
     
Store dry at 2-8 C�
Soluble in water
CAS 64485-93-4
R: 42/43 S: 22-24/25
 

Chloramphenicol C11H12Cl2N2O5=323.1
 
 Reference Number Pack Size

GBP (£)
 CLA01 25 g 22.00
 CLA02 100 g 50.00
     
Store dry at Room temperature
Slightly soluble in water (2.5 g/L)
Soluble in ethanol
R+S
 

Doxycycline Hyclate C22H24N2O6.HCl.�(H20).�(C2H6O)=512.94

Doxycycline is a bacteriostatical Tetracycline like antibiotic. The antibiotic is effective against both gram-positive and gram-negative bacteria. It binds reversible to the ribosomal 30 S unit, preventing binding of aminoacyl transfer RNA and hence inhibiting protein synthesis.

Doxycycline is an effective repressor of the TetO7 promoter system.
Media containing 10 micro-gram Doxycycline effectively repress the TetO7 promoter.

 
 Reference Number Pack Size

GBP (£)
 DOX01 1 g 9.50
 DOX05 5 g 18.75
 DOX10 10 g 28.50
 DOX25 25 g 61.50
     
 Specifications  
 Doxycycline Hyclate
 Doxycycline hydrochloride hemi-ethanolate hemihydrate
 Purity >98%
   
Store dry at 2-8 C�
Soluble in water
Protect against light
R: 20/21/22-40 S: 22-36/37/39-45

DTT Dithiotreitol C14H10O2S2=154.2
 
 Reference Number Pack Size

GBP (£)
 DTT005 5 g 11.25
 DTT010 10 g 18.75
 DTT025 25 g 41.25
 DTT100 100 g 131.25
     
Store dry at 2-8 C�
Soluble in water
Hygroscopic, protect against moisture
CAS 3483-12-3
R: 21/22-36/37/38 S: 26-36
 

EDTA Disodium C10H14N2O8Na2.2H2O = 372.2
EDTA Na2.2H2O
Ethylenediaminetetra-acetate Disodium Dihydrate
 
 Reference Number Pack Size

GBP (£)
 EDTA250 250 g 7.20
 EDTA500 500 g 12.00
 EDTA1000 1 kg 20.00
     
 Specifications  
 Purity >99%

 
Store dry at room temperature
Soluble in water (20 C�. 100g/L)
Hygroscopic, protect against moisture
CAS 6381-92-6
R: 36/37/38 S: 26-36/37/39

G-418 DiSulphate C20H40N4O10.2H2SO4=692.7

G-418 is a member of the large family of Aminoglycoside antibiotics and has a molecular structure almost like Gentamycin. The antibiotic is an irreversible inhibitor of protein synthesis. Due to its structure is capable of binding to both prokaryotic and eukaryotic ribosomes and inhibiting protein synthesis and generating errors in the transcription of the genetic code.

G-418 can by inactivated by NPTII or 3�APH. The hydroxyl group present at the 3� position of G-418 is phosphorylated by NPTII. The resulting steriometric change of the molecular structure of the antibiotic prevents it from binding at its ribosome binding site.
 
 Reference Number Pack Size

GBP (£)
 G4181 1 g 15.00
 G4185 5 g 75.00
     
 Specifications  
 Character Fine white powder
 Solubility Freely soluble in water
 Specific Optical Rotation +104� ~ +121�
 Water <6%
 Absorbance 570 nm <0.10
 Absorbance 280 nm <0.015
 NH4+ < 1.0%
 pH 5.5 � 0.5
 Thin Layer Chromatogram One Spot
 Potency >720 �g/mg
   
Store at room temperature
CAS 108321-42-2
R: 20/21/40/61 S: 22

G-418 Solution C20H40N4O10.2H2SO4=692.7

G-418 is a member of the large family of Aminoglycoside antibiotics and has a molecular structure almost like Gentamycin. The antibiotic is an irreversible inhibitor of protein synthesis. Due to its structure is capable of binding to both prokaryotic and eukaryotic ribosomes and inhibiting protein synthesis and generating errors in the transcription of the genetic code.
1 Bottle contains 20 ml G-418 Solution 50 mg/ml.
 
 Reference Number Pack  Size

GBP (£)
 G4181S 1 x 20 ml 30.00
 G4185S 5 x 20 ml 150.00
 
 Specifications  
 Solubility Freely soluble in water
 Specific Optical Rotation +104� ~ +121�
 Water <6%
 Absorbance 570 nm <0.10
 Absorbance 280 nm <0.015
 NH4+ < 1.0%
 pH 5.5 � 0.5
 Thin Layer Chromatogram One Spot
 Potency >720 units/mg
 Water Purity Used
 Resistivity at 25� C.    18.2 M
 Bacterial endotoxin <0.001 EU/ml
 TOC 1-3 ppb
 Bacteria < 0.1 CFU/ml
 Bacterial endotoxin

< 0.001/ml
 RNase and DNase Removed
   
Store at room temperature
CAS 108321-42-2
R: 20/21/40/61 S: 22

Gentamicin Sulphate

 Reference Number Pack Size

GBP (£)
 GEN05 5 g 9.00
 GEN25 25 g 21.00
     
 Specifications  
 Potency Approximately 640 units/mg
   
Store dry at room temperature
Soluble in water
CAS 1405-41-0
R: 36/38-42/43 S: 22-36/37/39-45

HEPES C8H18N2O4S=238.3

 Reference Number Pack Size

GBP (£)
 HEPES01 100 g 15.00
 HEPES03 250 g 24.00
 HEPES05 500 g 43.00
 HEPES10 1 kg 75.00
 HEPES60 6 kg 420.00
     
 Specifications  
 HEPES >99.5%
 Loss on Drying (105 �C, 4hr) <0.5%
 Water Content (By KF) <0.5%
 Infrared Complies
 pH 1% in water 4.8-5.6 (25�C)
 Solubility 1M in water Clear and colourless solution
 Residue on ignition <0.1%
 A260, 1M in water <0.045
 A280, 1M in water <0.035
 A420, 1M in water <0.20
 Heavy Metals <5 ppm
 pKa at 20�C 7.35-7.69
   
Store dry at room temperature
Soluble in water
CAS 7365-45-9
R: 36/37/38 S: 26

Hydroxyurea DNA replication inhibitor causing deoxyribonucleotide depletion CH4N2O2=76.05

Hydroxyurea is an anti-neoplastic which Inactivates ribonucleoside reductase by forming a free radical nitroxide that binds a tyrosyl free radical in the active site of the enzyme. This blocks the synthesis of deoxynucleotides, which inhibits DNA synthesis and induces synchronization or cell death in S-phase.

 Reference Number Pack Size

GBP (£)
 HDU0025 25 g 82.00
 HDU0100 100 g 280.00
 HDU0250 250 g 644.00
     
 Specifications  
 Appearance White Crystalline Powder
 Content by HPLC >97.5
 Water <0.5%
 Related substances <0.2%
 Residue on ignition <0.1%
 Heavy metals <10ppm
 Residue on ignition <0.1%
   
CAS 127-08-1
R: 46-63 S: 53-36/37-45

Hygromycin B (powder) C20H37N3O13=527.0

 Reference Number Pack Size

GBP (£)
 HYG0500 500 mg 28.90
 HYG1000 1 g 47.60
 HYG5000 5 g 214.40
     
 Specifications  
 Appearance White crystalline powder
 Identification (FTIR) Positive
 Solubility (100 mg/L) Clear and colourless solution
 Purity (HPLC) >92%
 Potency >1000 �g/mg
 Heavy Metals <20 ppm
 Specific rotation +22.1�
 Endotoxin <10 EU/mg
   
CAS 31282-04-09
R: 26/27/28-37/38-41 S: 23-26-36/37/39-45

IPTG Dioxane free  Isopropyl-β-D-1-Thiogalactoside C9H18O5S=238.3
 
 Reference Number Pack Size

GBP (£)
 IPTG001 1 g 6.00
 IPTG005 5 g 18.75
 IPTG010 10 g 33.75
 IPTG025 25 g 78.75
 IPTG100 100 g 252.00
 IPTG250 250 g 510.00
     
 Specifications  
 Purity (HPLC) 99.9%
 Purity (TLC) One Spot
 IR Conform standard
 Solubility (5%, H2O) Clear and colourless solution
 pH (5%, H2O) 6.0
 Optical rotation (C=1, H2O) -32.4�
 Melting point 111.5 - 112.4 C�
 Water KF 0.1%
 Dioxane (GLC)* <1 ppm
 * Not used in manufacturing process
   
Store dry at 2-8 C�
Soluble in ethanol and water
CAS 367-93-1
S: 22-24/25

Kanamycin Monosulphate C18H36N4O11H2SO4=582.6
 
 Reference Number Pack Size

GBP (£)
 KAN0005 5 g 12.00
 KAN0025 25 g 48.00
     
Store dry at room temperature
Soluble in water
CAS 25389-94-0
R: 61 S: 45-53
 

L(+)- Seleno Methionine C5H11NO2Se=196.1

 Reference Number Pack Size

GBP (£)
 SLM002 1 g 22.00
 SLM005 5 g 103.00
 SLM010 10 g 196.00
 SLM025 25 g 468.00
     
 Specifications  
 Appearance White crystalline powder
 IR Conform
 TLC Conform
 Melting point 263-266�C
 Optical rotation
 (C=1, 1N HCl)		 between +18.0 and +19.0
 Assay (titration) >99%
 Moisture <0.5%
 Selenium content (ICP or combustion): between 39 and 41% ( 40.2% theoretical)
 Optical purity minimum 99%  L-isomer and max. 1% D-isomer (HPLC or GC-MS)
 Particle size 60-80 mesh
   
CAS 3211-76-5
R: 62-36/37/38 S: 26-36

MES Monohydrate 2-(N-Morpholino) Ethanesulfonic acid C6H13NO4S.H2O=213.2

 Reference Number Pack Size

GBP (£)
 MES01 100 g 19.00
 MES02 250 g 45.00
 MES03  500 g 82.50
 MES04 1 kg 150.00
 MES05  6 x 1 kg 810.00
     
 Specifications  
 Appearance White Crystalline Powder
  Assay (Titration) ≥99%
  Water Content 8.0-8.9%
 pH 1% Di HB2BO 3.5-4.5
  Solubility 0.1M water Clear Colourless Solution
 Residue On Ignition

≤0.1%

 AB280B, 0.5M water

≤0.020
 AB260B, 0.5M water

≤0.025

 pKa 25

 5.9-6.3
 Heavy metals (Pb)

≤5ppm
   
Store dry at room temperature
Soluble in water
R+S

MES - SDS Running Buffer 20 X sterile RNAse free stock solution

 Reference Number Pack Size

GBP (£)
 MES-SDS0500 500 ml 22.00
 MES-SDS1000 1 L 42.00
 MES-SDS5000 5 L 200.00
     

After diluting 50 ml MES-SDS 20X into 950 ml demi water a 1X MES-SDS Running buffer is

prepared with a concentration of 50 mM MES, 50 mM TRIS base, 3.47 mM SDS and 1 mM EDTA.
 Specifications  
MES 1 M 195.2 g/L
TRIS 1 M 121.1 g/L
SDS 69.3 mM 20 g/L
EDTA Na2 20.5 mM 7.6 g/L
 

MOPS 4-Morpholino propanesulfonic acid C7H15NO4S=209.3

 Reference Number Pack Size

GBP (£)
 MOPS01 100 g 16.80
 MOPS02 250 g 25.00
 MOPS03 500 g 47.00
 MOPS04 1 kg 92.00
 MOPS05 6 x 1 kg 525.00
     
 Specifications  
 Appearance White crystalline powder
 Assay (Titration, Dry Base) ≥99.0%
 Water Content by KF ≤1%
 Infrared Complies
 Solubility 1M water Clear colourless solution
 pH 1% Di H2O 3.6 - 4.4 (25�C)
 A280, 1M water ≤0.10
 A260, 1M water ≤0.15
   
Store dry at room temperature
Soluble in water
CAS 1132-61-2
R: 36/37/38 S: 26-36

MOPS - SDS Running Buffer 20 X sterile RNAse free stock solution

 Reference Number Pack Size

GBP (£)
 MOPS-SDS0500 500 ml 22.00
 MOPS-SDS1000 1 L 42.00
 MOPS-SDS5000 5 L 200.00
     

After diluting 50 ml MOPS-SDS 20X into 950 ml demi water a 1X MOPS-SDS Running buffer is prepared with a concentration of 50 mM MOPS, 50 mM TRIS base, 3.47 mM SDS and 1 mM EDTA.
 Specifications  
MOPS 1 M 209.3 g/L
TRIS 1 M 121.1 g/L
SDS 69.3 mM 20 g/L
EDTA Na2 20.5 mM 7.6 g/L
 

Phosphate Buffered Saline pH 7.4 premix

 Reference Number Pack Size

GBP (£)
 PBS10L 10 L pack
(99.3 g)		 4.50
 PBS20L 20 L pack
(198.6 g)		 7.60
 PBS100L 10 X 10 L pack
(993 g)		 38.00
     

Reliable, quick and no pH adjustment necessary. A 10l pack in one litre is 10X, at this strength the ph is around 6.8/6.9, do not adjust this pH as on dilution to 1X the pH automatically adjusts to 7.4 which we determine during production.

 
 
R: 36/37/38   S: 26,36

TAE Buffer 50 X sterile stock solution

 Reference Number Pack Size

GBP (£)
 TAE0500 500 ml 10.80
 TAE0301 1 L 18.80
 TAE0305 5 L 69.80
     

After diluting 20 ml TAE Buffer 10X into 980 ml demi water a TAE 1X solution is prepared with

a concentration of 40 mM Tris base, 20 mM Glacial Acetic acid and 1m Na2EDTA.
 Specifications  
TRIS 2.0 M 242.0 g/L
Acetic Acid 1.0 M 60.0 g/L
Na2EDTA 0.05 M 20.3 g/L
 

TBE Buffer 10 X sterile stock solution

 Reference Number Pack Size

GBP (£)
 TBE0500 500 ml 9.80
 TBE0201 1 L 16.80
 TBE0205 5 L 59.80

After diluting 100 ml TBE Buffer 10X into 900 ml demi water a  1X TBE solution is prepared with

a concentration of 89 mM Tris base, 89 mM Borate and 2 mM Na2EDTA.

 
 Specifications  
TRIS 0.9 M 108.0 g/L
Boric acid 0.9 M 55.0 g/L
Na2EDTA 0.02 mM 8 g/L
         
 
 

TRIS Ultra Pure 99.9% C4H11NO3=121.1

 Reference Number Pack Size

GBP (£)
 TRIS01 1 kg 26.00
 TRIS06 6 x 1 kg 144.00
     
 Specifications  
 Purity

99.9~101.0%
 Solubility (0.1M, Water)

Clear
 APHP Color,20% Aqueous solution

<10#
 Melting point

168.5~171.5
 pH-value(5%; water)

10.0~11.5
 In water insoluble

<0.005%
 Abs.@280nm; 10%; 1cm; water

<0.03
 Abs.@260nm; 10%; 1cm; water

<0.06

 Loss on drying (105�C,3h)

<0.3%
 Residue after Ignition

<0.1%

 Heavy Metals

<0.0005%
 Chloride (Cl)

<0.0002%

 Sulfate (SO4)

<0.0005%
 As (Arsenic)

<0.0003%

 Ca (Calcium)

<0.0005%
 Cu (Copper)

<0.0005%

 Fe (Iron)

<0.0001%
 Mg (Magnesium)

<0.0005%

 Mn (Manganese)

<0.0005%
 Pb (Lead)

<0.0002%

 Zn (Zinc)

<0.0005%
 Appearance

White crystalline powder
   
CAS 77-86-1
Store dry at room temperature (18-25 �C)
R: 36/37/38
S: 26-36

X-Gal 5-Bromo-4-chloro-3-indolyl-β-D-galactopyranoside C14H15BrClNO6=408.6
 
 Reference Number Pack Size

GBP (£)
 XGAL001 1 g 16.00
 XGAL005 5 g 76.00
 XGAL010 10 g 156.00
     
 Specifications  
 Purity (HPLC) 99.2%
 Purity (TLC) >99%
 Water KF 0.2%
 Optical rotation
 (C=1, DMF:H2O=1:1))		 -61.1%
 
 Solubility (Sol., 2% DMF) Clear and colourless solution
 1H-NMR Conforming to structure
   
Store dry at 2-8 C�
Allow bottle to stand to room temperature before opening
Soluble in DMSO and DMF
Hygroscopic, protect against moisture
Store dark, protect against light
CAS 7240-90-6
S: 22-24/25
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